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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
U2AF2
All Species:
22.42
Human Site:
S407
Identified Species:
44.85
UniProt:
P26368
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P26368
NP_001012496.1
475
53501
S407
E
D
V
R
D
E
C
S
K
Y
G
L
V
K
S
Chimpanzee
Pan troglodytes
XP_530073
713
78555
S645
E
D
V
R
D
E
C
S
K
Y
G
L
V
K
S
Rhesus Macaque
Macaca mulatta
XP_001091568
467
51268
S399
E
D
V
R
D
E
C
S
K
Y
G
L
V
K
S
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P26369
475
53499
S407
E
D
V
R
D
E
C
S
K
Y
G
L
V
K
S
Rat
Rattus norvegicus
Q63285
419
46487
L360
K
Y
G
P
V
V
S
L
L
V
P
K
E
N
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080595
456
51328
G388
E
D
V
R
D
E
C
G
K
Y
G
A
V
K
S
Zebra Danio
Brachydanio rerio
NP_991252
475
53612
S407
E
D
V
K
E
E
C
S
K
Y
G
Q
V
K
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24562
416
46636
V357
K
Y
G
V
V
R
S
V
E
I
P
R
P
I
E
Honey Bee
Apis mellifera
XP_623055
432
48801
V373
K
Y
G
V
V
R
S
V
E
I
P
R
P
I
E
Nematode Worm
Caenorhab. elegans
P90978
496
55412
S429
E
D
V
R
D
E
C
S
K
Y
G
I
V
R
S
Sea Urchin
Strong. purpuratus
XP_001189425
444
50005
Q377
E
D
V
K
E
E
C
Q
K
Y
G
Q
V
R
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8L716
589
66297
G519
E
D
M
R
Q
E
G
G
K
F
G
N
L
V
N
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
53.4
87.5
N.A.
N.A.
99.7
20
N.A.
N.A.
N.A.
92
86.3
N.A.
66.7
66.7
51.4
62.9
Protein Similarity:
100
57.2
89.2
N.A.
N.A.
99.7
37.6
N.A.
N.A.
N.A.
94.7
92.2
N.A.
77
77.8
62.5
75.5
P-Site Identity:
100
100
100
N.A.
N.A.
100
0
N.A.
N.A.
N.A.
86.6
80
N.A.
0
0
86.6
66.6
P-Site Similarity:
100
100
100
N.A.
N.A.
100
6.6
N.A.
N.A.
N.A.
86.6
93.3
N.A.
13.3
13.3
100
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% A
% Cys:
0
0
0
0
0
0
67
0
0
0
0
0
0
0
0
% C
% Asp:
0
75
0
0
50
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
75
0
0
0
17
75
0
0
17
0
0
0
9
0
17
% E
% Phe:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% F
% Gly:
0
0
25
0
0
0
9
17
0
0
75
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
17
0
9
0
17
0
% I
% Lys:
25
0
0
17
0
0
0
0
75
0
0
9
0
50
0
% K
% Leu:
0
0
0
0
0
0
0
9
9
0
0
34
9
0
0
% L
% Met:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
9
0
9
9
% N
% Pro:
0
0
0
9
0
0
0
0
0
0
25
0
17
0
9
% P
% Gln:
0
0
0
0
9
0
0
9
0
0
0
17
0
0
0
% Q
% Arg:
0
0
0
59
0
17
0
0
0
0
0
17
0
17
0
% R
% Ser:
0
0
0
0
0
0
25
50
0
0
0
0
0
0
67
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
67
17
25
9
0
17
0
9
0
0
67
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
25
0
0
0
0
0
0
0
67
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _